Early Life and Education: The book delves into Che Guevara's early life, upbringing in Argentina, and his education as a medical student, shedding light on the formative years that shaped his worldview.

Role in the Cuban Revolution: It provides a detailed account of Guevara's involvement in the Cuban Revolution alongside Fidel Castro, including his military contributions and leadership during key battles.

Internationalism and Guerrilla Warfare: Guevara's commitment to internationalism and his advocacy for guerrilla warfare as a strategy for revolutionary change are explored in-depth, drawing from his experiences in various countries.

Role in Cuban Government: The book discusses Guevara's role in the Cuban government, where he served in various capacities, including as Minister of Industry. It examines his efforts to implement economic and social reforms.

Struggles in the Congo and Bolivia: Guevara's attempts to export the revolutionary model to other countries, particularly his experiences in the Congo and Bolivia, are covered. The book explores the challenges he faced and the ultimate failure of these ventures.

Ideological Evolution: Anderson analyzes the evolution of Guevara's political and ideological beliefs over time, including his Marxist-Leninist convictions and his critique of Soviet-style socialism.

Relationships with Other Revolutionary Figures: The book delves into Guevara's relationships with other revolutionary leaders, including Fidel Castro, Camilo Cienfuegos, and other key figures in the Cuban Revolution.

Personal Life and Family: It provides insights into Guevara's personal life, including his relationships, family dynamics, and the challenges of balancing revolutionary activities with personal responsibilities.

Legacy and Iconography: Anderson explores the enduring legacy of Che Guevara, examining how he became an iconic symbol of revolution and resistance worldwide, transcending his role as a historical figure.

Controversies and Criticisms: The book doesn't shy away from addressing controversies and criticisms surrounding Guevara, including his role in executions, his confrontations with dissent within the revolutionary ranks, and the complexities of his legacy.